SURPRISE 49ers Cut Candidates After 2025 NFL Draft: Isaac Guerendo & Malik Mustapha Headline Shocking Roster Shake-Up

The San Francisco 49ers have set the NFL rumor mill ablaze after the 2025 NFL Draft, with a wave of speculation and heated debate erupting over a list of surprise cut candidates. Most shocking among them: rookie running back Isaac Guerendo and promising safety Malik Mustapha. As training camp approaches, these unexpected names are fueling passionate arguments among fans, analysts, and insiders-making this one of the most talked-about storylines of the offseason.

Isaac Guerendo: From Draft Day Darling to Roster Bubble?

Guerendo, a fourth-round pick who wowed scouts with his speed and explosiveness at the combine, was expected to add a new dimension to the 49ers’ backfield. But with Christian McCaffrey entrenched as the starter and Elijah Mitchell and Jordan Mason providing proven depth, Guerendo suddenly finds himself fighting for a roster spot. Critics argue that the 49ers’ crowded running back room and special teams needs could push Guerendo out, while supporters insist his upside is too high to let go. The debate is raging: Is this a classic case of a draft pick who never gets a real shot, or will Guerendo’s preseason performance force the coaches’ hands?

Malik Mustapha: Defensive Gem or Odd Man Out?

Mustapha, a hard-hitting safety with a reputation for making game-changing plays at Wake Forest, was seen as a steal for the 49ers’ secondary. However, the team’s aggressive moves in free agency and the draft have created a logjam at the safety position. With Talanoa Hufanga returning from injury and Ji’Ayir Brown emerging as a future star, Mustapha’s path to the 53-man roster is suddenly murky. Fans are fiercely divided: some believe Mustapha is a special teams ace and developmental project worth keeping, while others see him as a likely practice squad stash or even a trade candidate.

Social Media Meltdown & Fan Reactions

49ers Twitter and Reddit are in overdrive, with fans dissecting every roster move and preseason rumor. Is the front office making a huge mistake by potentially cutting talented rookies before they get a chance to prove themselves? Or are these tough decisions necessary for a team with Super Bowl aspirations and a loaded roster? The conversation is spilling out into podcasts, YouTube debates, and viral TikTok clips-everyone has an opinion, and no one can agree.

What’s Next for the 49ers?

With the preseason looming and the final cutdown to 53 players set for late August, the pressure is on for Guerendo, Mustapha, and other bubble players to make their case. Will the 49ers risk losing young talent to waivers, or will they stick with established veterans in pursuit of another NFC title run? One thing is certain: these surprise cut candidates have turned the 49ers’ offseason into a lightning rod for controversy, viral debate, and endless speculation.

Where do you stand, Faithful? Are Guerendo and Mustapha victims of a numbers game, or will they defy the odds and make the final roster? Sound off and share your take-this is the 49ers story everyone’s talking about in 2025!