On Monday night, football fans will be treated to a thrilling rematch as the Detroit Lions face off against the San Francisco 49ers in what promises to be a dramatic showdown. This Week 17 matchup revisits the setting of last season’s NFC Championship Game, where the Lions’ Super Bowl aspirations were dashed on the 49ers’ home turf. Returning to San Francisco evokes memories of heartbreak but also fuels Detroit’s hunger for redemption, adding a compelling narrative to an already high-stakes game.

Here are six key Lions players to watch as they take the field in this Monday Night Football finale of the 2024 season:

Jahmyr Gibbs: The Offensive Spark

With David Montgomery sidelined, rookie sensation Jahmyr Gibbs has stepped up as the centerpiece of Detroit’s rushing attack. Fresh off a dazzling performance against the Chicago Bears where he amassed 154 all-purpose yards on 27 touches, Gibbs is poised to shine under the bright lights. San Francisco’s defense has shown vulnerability, as evidenced by Miami Dolphins’ Devon Achane torching them for 120 rushing yards and a touchdown just last week.

Gibbs brings a dynamic dual-threat capability, equally dangerous on the ground and as a receiver. Against a 49ers defense that occasionally struggles to contain explosive playmakers, Gibbs is primed for another standout performance, with the potential to exceed 100 all-purpose yards and find the end zone.

Jameson Williams: The Deep Threat

Jameson Williams is having a breakout year, and his career-best campaign positions him as a pivotal weapon for quarterback Jared Goff. With 1,000 receiving yards within reach for the first time in his career, Williams has proven to be more than just a speedster—he’s a reliable playmaker.

Against the Bears last week, Williams showcased his game-breaking ability with 143 receiving yards and a touchdown on just five receptions. While he may not replicate those numbers against San Francisco’s stingy secondary, his ability to stretch the field could prove vital. The 49ers often deploy single-high safety coverage, a look that Goff and Williams can exploit for a big play or two. Expect Williams to finish with at least five catches and a significant long reception that keeps the defense honest.

Amon-Ra St. Brown: The Consistent Force

Amon-Ra St. Brown has cemented his status as one of the NFL’s elite wide receivers. Entering his fourth season, St. Brown has delivered yet another stellar year, surpassing 100 catches, 1,100 yards, and double-digit touchdowns for the second consecutive season. His consistency and versatility make him a nightmare for opposing defenses.

In recent weeks, St. Brown has been a cornerstone of Detroit’s offense, including a 14-catch, 193-yard outburst against the Buffalo Bills and a solid 70-yard performance against Chicago. On Monday night, look for Goff to lean heavily on his trusted target, especially over the middle of the field, where St. Brown thrives. Six receptions and 70 yards are well within reach as St. Brown continues to lead the Lions’ passing game.

Brian Branch: The Defensive Playmaker

Brian Branch has emerged as a cornerstone of Detroit’s defense in just his second year. With his versatility to play both safety and nickel corner, Branch has been a key factor in the Lions’ success. This season, he has tallied 96 tackles, 15 passes defended, four interceptions, and a forced fumble, earning an impressive 80.4 grade from Pro Football Focus.

On Monday, Branch will be tasked with containing San Francisco’s breakout slot receiver Jauan Jennings, who has racked up 856 yards and six touchdowns this season. It’s a tall order, but Branch’s instincts and coverage skills make him the Lions’ best bet to disrupt Jennings’ rhythm and limit his production.

Al-Quadin Muhammad: The Unsung Hero

Al-Quadin Muhammad has been a revelation for the Lions this season, stepping up in the absence of injured pass-rushers Aidan Hutchinson and Marcus Davenport. After starting the year on the practice squad, Muhammad has become a key contributor to Detroit’s defensive line.

In this matchup, Muhammad’s ability to generate pressure will be critical against 49ers quarterback Brock Purdy. San Francisco’s offense thrives when Purdy has time to operate, and disrupting his timing will be essential for the Lions to secure a victory. Look for Muhammad to team up with Za’Darius Smith to apply consistent pressure off the edge.

Jack Campbell: The Defensive General

As the leader of the Lions’ defense, linebacker Jack Campbell will play a pivotal role in Monday night’s clash. Campbell’s responsibilities will include keeping tabs on Brock Purdy, covering the ever-dangerous George Kittle, and containing the 49ers’ rushing attack led by Isaac Guerendo.

Campbell’s matchup with Kittle will be particularly critical. The two-time All-Pro tight end is coming off an eight-catch, 106-yard performance against the Dolphins and remains a key weapon in San Francisco’s offense. However, Campbell has proven capable of rising to the occasion, amassing 116 tackles this season and earning a solid 75.4 PFF grade. His ability to neutralize Kittle could swing the game in Detroit’s favor.

This Monday Night Football showdown is more than just a game; it’s a statement opportunity for the Lions as they seek to solidify their playoff positioning and exorcise the demons of last year’s NFC Championship loss. With key players like Gibbs, Williams, and Branch leading the charge, Detroit has the tools to leave San Francisco victorious and send a message to the rest of the league. Let the battle begin.