The Detroit Lions are bracing to lose one or both of their coordinators to head-coaching opportunities this offseason, and at least one assistant could be in line for a promotion elsewhere, too.

Lions defensive backs coach Deshea Townsend interviewed with the San Francisco 49ers for their vacant defensive coordinator job, the 49ers announced Thursday.

Townsend is in his first season with the Lions after spending two years as cornerbacks coach and defensive pass game coordinator with the Jacksonville Jaguars. In Detroit, he oversaw a secondary that played among the most man-to-man coverage in the NFL.

The Lions finished 30th in the league in pass defense this season at 244 ypg allowed, but tied for the fifth-most interceptions (16). Last week, they shut down Justin Jefferson and the Minnesota Vikings’ high-powered offense to improve to 15-2, win the NFC North and get a first-round playoff bye.

Lions offensive coordinator Ben Johnson, defensive coordinator Aaron Glenn and front office executive Chris Spielman also are expected to interview for promotions with other teams in the coming days.

Johnson will meet virtually with the New England Patriots, Chicago Bears, Las Vegas Raiders and Jacksonville Jaguars about their head-coaching positions. The Bears, Raiders, Jaguars, Patriots, New Orleans Saints and New York Jets put in interview requests for Glenn for their head coach. And Spielman plans to interview for the Jets’ general manager job.

The 49ers also interviewed Dearborn native and former Jets head coach Robert Salah for their defensive coordinator position Thursday. Saleh, the 49ers’ defensive coordinator in 2017-20, is considered the favorite for the job.

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Townsend played 13 NFL seasons from 1998-2010 with the Pittsburgh Steelers and Indianapolis Colts as a defensive back.