Detroit (12-1) is the odds-on favorite to win the NFL title, according to BetMGM, and Buffalo (10-3) is not far behind as one of the top contenders.
The Bills have won six of the past seven meetings with the Lions, losing only in 2006 in Detroit.
Head Coach Dan Campbell was aggressive on fourth down in Detroit’s win over the Packers, trying to keep the team’s injury-depleted defense off the field. He went for it on fourth down five times, with the Lions converting four attempts.
A few key defensive players who have been injured are likely to return Sunday.
Injuries
Lions
Lions defensive tackle D.J. Reader (shoulder) and defensive linemen Levi Onwuzurike (hamstring) and Josh Paschal (knee) were full participants in practice Friday after missing Week 14’s game against Green Bay.
Offensive tackle Taylor Decker (knee) defensive tackle Alim McNeill (concussion) practiced in full on Thursday and Friday, moving closer to playing after being out against Chicago on Thanksgiving.
Linebacker Trevor Nowaske (concussion) has been ruled out, according to the team.
Bills
Bills cornerback Rasul Douglas (knee) has been ruled out, the team says.
Safety Taylor Rapp (shoulder, neck) did not practice Wednesday or Thursday and is questionable.
Tight end Dalton Kincaid, who has missed three games with a knee injury, and wide receiver Keon Coleman, who’s missed four games with an injured right wrist, are in position to return against Detroit.
Kickoff is at 4:25 p.m. Watch below for live updates.
Gibbs scores receiving touchdown
The Lions have cut the deficit to 10 after a 12-yard touchdown reception by Jahmyr Gibbs.
Buffalo leads Detroit 38-28 with 12 minutes left in the game.
Bass kicks 50-yard field goal
Bills kicker Tyler Bass hit a 50-yard field goal with 14:02 left in the fourth quarter to increase Buffalo’s lead to 38-21 over the Lions.
St. Brown scores 66-yard touchdown
Detroit Lions receiver Amon-Ra St. Brown scored a 66-yard touchdown reception with 1:41 left in the third quarter.
The Lions trail the Buffalo Bills 35-21.
Allen throws passing touchdown, increases lead for Bills
Buffalo Bills quarterback Josh Allen threw a 3-yard touchdown pass to receiver Khalil Shakir with 3:31 left in the third quarter.
The Bills now lead the Detroit Lions 35-14.
Buffalo starts second half strong with rushing touchdown
Bills running back James Cook scored a 41-yard rushing touchdown with just over 13 minutes left in the second quarter.
The Bills now lead the Detroit Lions 28-14.
Bills, Lions trade missed field goals
Bills kicker Tyler Bass and Lions kicker Jake Bates both missed field goals with less than two minutes in the first half.
Bass missed a 24-yard attempt and Bates missed a 52-yard attempt.
Lions lineman scores touchdown
Offensive tackle Dan Skipper has scored a touchdown — the first of his career.
Skipper scored off a 9-yard play-action pass from Jared Goff with 3:01 left in the second quarter.
The Lions trail the Buffalo Bills 21-14.
Bills increase lead after rushing touchdown from Cook
The Buffalo Bills are now leading 21-7 over the Detroit Lions after a 6-yard rushing touchdown from James Cook.
Cook scored with 8:15 left in the second quarter.
Patrick gets Lions on the board
The Detroit Lions are on the scoreboard after a 12-yard touchdown reception by Tim Patrick.
The Lions trail the Buffalo Bills 14-7 with 13:36 left in the second quarter.
Allen scores again for bills
The Bills now lead 14-0 after Josh Allen’s second rushing touchdown of the afternoon.
Allen scored on a 4-yard run with 2:01 left in the first quarter.
Josh Allen scores rushing touchdown for Bills
Buffalo Bills quarterback and MVP-favorite Josh Allen scored the first points of the game with a 1-yard rushing touchdown.
The Bills lead the Detroit Lions 7-0 with just under 11 minutes left in the first quarter.
Lions looking for deep playoff run
There are still four games left in the season, but the Detroit Lions have already punched their tickets to the playoffs.
Despite clinching a spot, Coach Dan Campbell says they’re looking for more.
