The Lions are holding out hope that running back David Montgomery will be able to play again this season, but his return will not come against the 49ers on Monday night.
Montgomery was ruled out of their Week 17 game on the team’s final injury report of the week. Montgomery has a knee injury and will be missing his second straight game.
The Lions also ruled out wide receiver Kalif Raymond. Raymond (foot) returned to practice this week, but will remain on injured reserve for at least another week.
Linebacker Jalen Reeves-Maybi (neck) is listed as questionable after a week of full practices. Cornerback Terrion Arnold (illness) and guard Graham Glasgow (knee) have no designations.